Infection with the human immunodeficiency virus (HIV), the cause of this disease, is felt to be present in more than 1 million people, with over 500,000 cases of Acquired Immunodeficiency Syndrome (AIDS) having been reported to the Center for Disease Control and Prevention. The use of marijuana in AIDS treatment as an antiemetic and appetite stimulant, especially when muscle wasting is prominent, remains controversial. Malignant Disorders remains an extremely common disease in the society, affecting over 8 million Americans and being responsible for approximately one out of every five deaths. There are a number of drugs that have been found to be helpful in relieving pain in persons with cancer, especially when neuropathic pain is present. Antidepressants provides additional analgesia in nerve pain and may result in lowering the dose of narcotic needed. Corticosteroids have been of most value in diminishing inflammation in the absence of infection, and in reducing elevated pressure in the central nervous system.