ABSTRACT

This chapter describes trade name, classification, approved indications for psychological disorders, available dosage forms, storage, and compatibility, usual dosage and administration, relative contraindications, and clinically significant drug interactions of Chlordiazepoxide. Periodic blood counts and liver function tests are recommended for patients who require long-term chlordiazepoxide pharmacotherapy. Generally, the acute signs and symptoms of anxiety may be rapidly controlled by intramuscular or intravenous chlordiazepoxide pharmacotherapy. Store chlordiazepoxide capsules and tablets in tightly closed child- and light-resistant containers at controlled room temperature. Chlordiazepoxide has sedative, hypnotic, and muscle relaxant actions. Long-term chlordiazepoxide pharmacotherapy, or regular personal use, may result in addiction and habituation. Concurrent chlordiazepoxide pharmacotherapy with opiate analgesics, other sedative-hypnotics, or other drugs that produce Central Nervous System (CNS) depression may result in additive CNS depression. Signs and symptoms of chlordiazepoxide overdosage include confusion, diminished reflexes, drowsiness, incoordination, and coma.