ABSTRACT

This chapter describes trade name, classification, approved indications for psychological disorders, available dosage forms, storage, and compatibility, usual dosage and administration, relative contraindications, and clinically significant drug interactions of Diazepam. Maternal use near term has been associated with expected pharmacologic actions among neonates, including hypotonia, low Apgar scores, poor feeding, and signs and symptoms of diazepam withdrawal. Avoid prescribing diazepam pharmacotherapy to women who are pregnant. Periodic blood counts and liver function tests are advised for patients who require long-term diazepam pharmacotherapy. Long-term diazepam pharmacotherapy rarely has been associated with jaundice and neutropenia. The usual recommended dosage for injectable diazepam pharmacotherapy for children and adults ranges from 2 to 20 mg intramuscularly or intravenously. The dosage prescribed depends on the indication for diazepam pharmacotherapy and the severity of the patient’s signs and symptoms. Long-term diazepam pharmacotherapy, or regular personal use, may result in addiction and habituation. Diazepam pharmacotherapy commonly has been associated with drowsiness, fatigue, and incoordination.