ABSTRACT
This chapter describes trade name, classification, approved indications for psychological disorders, usual dosage and administration, relative contraindications, clinically significant drug interactions, adverse drug reactions and overdosage of Morphine. Morphine pharmacotherapy is not recommended for women prior to labor unless potential benefits outweigh possible risks to the embryo, fetus, or neonate. Morphine is excreted into breast milk. The concentration of morphine in breast milk generally is higher than that in maternal blood. Prescribe morphine pharmacotherapy at regular intervals throughout the 24-hour day for the symptomatic management of pain. Among elderly patients, the volume of distribution is considerably smaller, and initial concentrations of morphine are, thus, correspondingly higher. Morphine generally is considered the prototype for all opiate analgesics and, thus, is the measure by which they are compared. Morphine has high abuse potential, and long-term morphine pharmacotherapy, or regular personal use, may result in addiction and habituation.
