ABSTRACT
This chapter explains the cellular origins and pathophysiology of common cancers and the pharmacological action of anti-cancer drugs.
Introduction
12.1 The physiology behind cancer — cell division DNA (deoxyribose nucleic acid) and protein synthesis DNA replication The cell cycle
12.2 The pathophysiology of cancer The epidemiology of cancer The development of cancer
12.3 Anti-cancer drugs — chemotherapy General principles of anti-cancer chemotherapy Fraction-kill hypothesis Combination therapy Side-effects of anti-cancer drugs Anti-cancer drugs during pregnancy Pharmacology of anti-cancer drug groups
References and further recommended reading Test yourself
The chapter contains some brief case studies and finishes with some self-test questions to enable you to be certain that you have understood the physiology, pathology and pharmacology of this important area.
