ABSTRACT
Early study of schizophrenia patients found low rates of OC symptom comorbidity. In a retrospective chart review of 1,000 schizophrenia patients, Jahrreiss (1926) found significant OC symptoms in only 1.1 %. Rosen (1957) performed a similar chart review of 848 schizophrenia patients and reported that 30 (3.5%) had prominent obsessions, compulsions, or both. Several methodologic limitations of these early studies, including lack of prospective evaluation and standardized diagnostic criteria for schizophrenia (possibly including patients with other psychoses), may have led to an underestimation of comorbid OC symptom rates. In a more rigorously designed retrospective study, Fenton and McGlashan (1986) reported that 21 of 163 patients (13%) meeting Diagnostic and Statistical Manual of Mental Disorders (3rd ed. [DSM-III]; American Psychiatric Association, 1980) criteria for schizophrenia also had OC symptoms.
