ABSTRACT

After completing this chapter, the reader should be able to:

define the terms ‘pharmacogenetics’ and ‘genetic polymorphism’;

describe how genetic polymorphism can affect drug responsiveness at the population level;

outline how genetic polymorphism can be tested for diagnostically;

in terms of the effects on drug treatment, compare responders and non-responders;

outline the relationship between genetic polymorphism and ethnicity;

outline the ethical considerations associated with pharmacogenetics.