ABSTRACT
After completing this chapter, the reader should be able to:
outline the normal physiology of the nephron;
describe the sites and mechanisms of action of the various types of diuretic;
list the high-efficacy diuretics, their uses and their adverse effects;
describe the use of thiazides and related drugs;
describe the use of potassium-sparing diuretics;
outline the problems associated with the use of diuretics;
describe the use of osmotic diuretics;
describe the use of urinary alkalinisers and acidifiers;
outline the treatment of diabetes insipidus.
