ABSTRACT

Self-stimulation can be obtained in dozens of brain regions, from the cerebral cortex (Routtenberg, 1971) to the medulla (Carter & Phillips, 1975), including all major brain divisions, such as hippocampus (Campbell, Milgram, & Christoff, 1980), basal ganglia (Phillips, Carter, & Fibiger, 1976), olfactory bulbs (Phillips & Mogenson, 1969), and cerebellar cortex (Ball, Micco, & Berntson, 1974). In each of these structures there are many more sites where self-stimulation cannot be obtained, however. Self-stimulation can be obtained in roughly 20% of rat brain tissue using 60-cycle sine-wave stimulation at currents up to 100 fLA.