Psychotherapy, very broadly, is an intervention approach that uses a range of techniques, in the context of a relationship between the therapist and patient, in order to facilitate changes. These changes encompass improved health and mental health, and enhanced positive functioning (Prochaska and Norcross 2013). Psychological treatment describes those interventions applied in a healthcare context (Barlow 2006). There is a large body of evidence supporting the efﬁ cacy and clinical utility of psychological treatments (Roth and Fonagy 2005), with many of these therapies established as ﬁ rst-line interventions for common mental health problems (e.g., panic disorder, depression). In recent decades, these treatments have had wider application to chronic health conditions, such as heart disease and back pain, with positive outcomes on clinical indices (Hoffman et al. 2007). Psychophysiological research has identiﬁ ed changes in autonomic nervous system functioning (Bonaz and Bernstein 2013) and brain blood ﬂ ow (Karlsson 2011) as potential biological mechanisms for symptom improvements with these “talk therapies”. While psychological interventions are wellestablished as efﬁ cacious in the functional gastrointestinal disorders (Ford et al. 2009), their clinical utility in inﬂ ammatory bowel disease (IBD) is less clear (Timmer et al. 2011).