chapter  21
Antidepressants and IBD
Pages 8

Antidepressants – including tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), monoamine oxidase inhibitors (MAOIs) and other atypical drugs, such as bupropion, mirtazapine, nefazodone and trazodone – are nowadays becoming the fi rst line treatment for depression and/or anxiety. The reasons for their widespread use include their accessibility, a relatively small cost and increasingly improved safety profi les. The result of this treatment, if effective, is apparent after only few weeks, which contrasts with a much longer waiting time in the case of psychotherapy.