ABSTRACT
Alzheimer's disease (AD) is a slow, progressive and a chronic neurodegenerative disease that results in loss of memory, cognition, language skills and drastic behavioural changes which cause 60–70% of dementia. The hyperphosphorylation of tau proteins leading to the formation of intercellular neurofibrillary tangles is one of the pathologies in AD. A handful of plant compounds displayed the ability to scavenge these free radicals, preventing oxidative damage and their effects were tested in the CNS, which could pave the way for AD treatment. The benefits offered by plants as AD therapeutics are immense: they are inexpensive, are taken as food supplements and contain fewer side effects. All the drugs currently available for AD are symptomatic and have their own limitations; they hardly have influence over the advancement of AD and cause side effects in patients. The neuroprotective potential of ginseng was validated in AD experimental models. P. ginseng has shown to be effective in the improvement of cognitive performance in patients.
