ABSTRACT
Magnetic nanoparticles (MNPs) are extensively used for applications in nanobiomedicine like gene therapy, chemotherapy, magnetic resonance imaging, contrast enhancement, protein therapy, tissue repair, magnetic hyperthermia therapy, and anticancer drug delivery. These applications necessitate MNPs to be colloidally stable in biological media. The goal of this chapter is to study the current advances in designing and surface engineering of MNPs for biomedical applications. The superparamagnetic nanoparticles stabilized by coating with biologically compatible polymers are analyzed using X-ray diffraction, transmission electron microscopy, zeta potential measurements, dynamic light scattering, superconducting quantum interference device magnetometry and inductively coupled plasma optical emission spectrometry, and cell viability measurements 58that indicate the toxicity of the developed system to typical cell lines. Here, we report the accelerated growth in the demand for surface modified MNPs as theranostic tools for application in the field of oncology and bionanomedicine.
