chapter  7
6 Pages


WithA. Šiber, P. Ziherl

If the most pleasurable moment in research is discovery, the second best is when one realizes that a given phenomenon is a reincarnation of something that is already known. By establishing these analogies, which are sometimes very evident and sometimes less so, we gradually build a system that helps us better understand the awe-inspiring diversity of nature. It all becomes even weirder and weirder at micrometer and nanometer scales. After all, life started from these length scales, spending three billion years there before exploring the multicellular ways of existence. It did have some time, therefore, to scrutinize the domain of the small. In addition to the increasingly more detailed and less invasive experimental techniques, the field often requires fresh and innovative theoretical approaches. It seems that many of the ideas discussed - apico-basal cell polarization, coupling between tissue curvature and cell division, fixed-volume constraints, etc., - can be exploited so as to establish such a control.