ABSTRACT
Regeneration of nerve has attracted much attention and because of the need to supply the variety of components to the elongation axon, the role of axoplasmic transport in these axons has been extensively studied. The major function of protein transport is to supply axonal components to maintain equilibrium along the whole length of the axon which is in a continually dynamic state due to varying rates of turnover of its constituent parts. The functioning axon and its terminals require a continual supply of membrane components, cytoskeletal elements, and enzymes for various functions. It is becoming increasingly obvious that fast axonal transport is a system whereby materials, packaged in vesicles or vacuoles, are carried to the axon, the axolemma, and the axon terminals. J. J. Bray showed that newly synthesized protein, when transported down an axon, returns by retrograde flow if it meets an obstruction.
