ABSTRACT
This chapter describes the size of the iron oxide particles is in the lower nanometer range, so that attraction is only achieved in a high-gradient magnetic field. Superparamagnetic particles can be removed from solution in a high-gradient magnetic field. The chapter also describes the preparation of magnetoliposomes colloids in which the iron oxide core is coated by phospholipids. Based on both theoretical considerations and experimental evidence, arguments will be presented which definitely prove that the phospholipids adopt a bilayer configuration. The chapter highlights the value of magnetoliposomes as hosts for membrane enzymes. The ultimate goal is to construct a bioreactor in which the resulting magnetoproteoliposomes are first captured in a high-gradient magnetic field and then a solution of substrate is passed over them. The unique potentialities of magnetoproteoliposomes are illustrated by the catalytic activity expressed in bioreactors.
