ABSTRACT
Osteogenesis (or ossification) is the process by which bone is formed. It refers to the formation of all components of bone. Calcification denotes mineralization of bone, i.e., deposition of calcium salts in the interstitial substance and collagen. The bone cells participating in bone formation are osteoblasts, which secrete the specific intercellular substance and collagen, which later may calcify. Two types of bone formation are known: intramembranous and endochondral. 1 , 2 Osteogenesis can be studied either from developing embryonic bone or through the process of fracture repair.
