ABSTRACT

The unrelated rhesus monkeys used were all imported from India in a number of shipments between 1965 and 1975. The related monkeys were all raised in the Primate Center TNO, employing a harem-type breeding system with approximately ten females per breeding male. Certain characteristics of DR antigens and the antisera defining them have been pub lished. It was shown by co-capping studies that Class II orIa antigens of rhesus mon keys are distinct from Class I or A and B locus antigens, and that Ia antigens are not associated with ß 2-microglobulin. As indicated, a number of Ia-like antigens identifiable on monkey lymphocytes are not controlled by the D-related (DR) locus. In the late 1970s, several rhesus "harems," each consisting of a few families, were typed with a limited number of TCs in order to study the segregation of the D antigens in families.