ABSTRACT
Iron and Human Disease is the first book to cover the three key aspects of human iron metabolism: the accumulation of iron in adults, iron as a limiting factor for tumor and infectious cell growth, and iron as a catalyst for oxygen free radical production. The book describes the hypotheses and findings related to the role of iron in cardiovascular disease (including reperfusion injury), cancer, aging, and autoimmune and neurodegenerative diseases. Other topics covered include the molecular biology and biochemistry of iron, the general principles governing iron balance, iron in the immune system and acute phase response, and new preventive and therapeutic strategies.
Iron and Human Disease will be a useful reference for biomedical investigators, physicians, nutritionists, and public health officials.
TABLE OF CONTENTS
part |83 pages
Part I: Chemistry and Molecular Biology of Iron and Iron-Binding Proteins
part |102 pages
Part II: Iron Accumulation and Metabolism in Humans
part |54 pages
Part III: Iron and Oxidative Stress
part |70 pages
Part IV: Roles for Iron in Cardiovascular Disease
part |127 pages
Part V: Roles for Iron in Other Common Diseases
part |61 pages
Part VI Implications for Prevention and Therapy