ABSTRACT

There have been several reviews of the glycoprotein hormone structures. The review by Ward 1 was directed at functional group substitutions in order to pinpoint essential structural elements. The review by Pierce and Parsons2 dealt with structural relationships and considered the then-available recombinant DNA studies on this group of hormones. Gordon and Ward3 provided an update on functional group studies, but limited it to the hormones interacting with the luteinizing hormone (lutropin, LH) receptor. In the same volume, Strickland et a1. 4

updated structural information on LH and human (h) chorionic gonadotropin (choriogonadotropin, CG). Bahl and WaghS reviewed the carbohydrate structures of the glycoprotein hormones. Fiddes and Talmadge6 reviewed the gene structure and evolution of the human glycoprotein hormones.