ABSTRACT

The nature of alkali metal transport across biological membranes is an area that has been extensively investigated in recent years. Inhibitory drugs and other agents have been used in these studies to dissect and isolate pharmacologically transport systems of interest. Information concerning the mechanism of transport, its modification by physiological conditions (either natural or experimentally imposed), and its interaction with these inhibitory molecules, can be derived by observing the effects that chemically well-defined analogues have upon these processes.