ABSTRACT
Salmonellosis in the human occurs in a wide variety of forms presenting a broad clinical spectrum. The disease may occur solely as an intestinal infection, termed salmonellosis or salmonella gastroenteritis, as a focal infection in any organ of the body, or as a systemic febrile infection. The clinical symptoms of the intestinal infection vary from asymptomatic, or no symptoms, to a most severe diarrhea with fever and nausea. Prolonged fever usually does not occur with infections other than those caused by Salmonella typhi, which is classified as an enteric fever. Because all persons differ in susceptibility to any infectious disease, and microorganisms are likely to differ considerably coming from different environments, it is most difficult to establish a minimum infective dose for any pathogen. Although it might seem desirable to establish a specific minimum infective dose for any pathogen, it is essentially an impossible task to establish one such dose for the Salmonella group.
