ABSTRACT

This conclusion presents some closing thoughts on the concepts covered in the preceding chapters of this book. The book examines the importance of chemical and genetic modification of natural polymers, in particular, proteins in the synthesis of biospecific and biosimulation materials. In the synthesis of truly biocompatible materials, in vivo tissue reconstruction on a synthetic polymer membrane was found to be most promising. In order to realize tissue generation on a polymer membrane, the membrane surface should be suitably modified from the viewpoint of organ engineering. In the synthesis of artificial enzymes, which are useful for chemical production and new therapeutic systems, protein engineering has been found to be an effective tool. Protein engineering is an extremely attractive technology and offers a variety of possibilities for the production of protein materials. The peptide fragment including the site for substitution with a nonnatural a-amino acid should be chemically synthesized. Other peptide fragments can be synthesized either chemically or biologically.