ABSTRACT
A major aspect of the action of hormones is their production in one tissue and their effect on a different tissue. These chemical mediators are most frequently transported by the blood and lymph. The excretion of specific hormones from the blood into the urine is quite understandable. As the science of anatomy evolved, it became apparent that some of the glands of the body appeared to have no ducts even though it appeared quite obvious that the glands did have a microscopic appearance suggestive of a secretory function. None of the hormones or their metabolites which occur in urine appear to perform any physiological function related to their urinary excretion. Urinary estrogen measurements provide one of the means of assessing the normalcy or the abnormalcy of the female menstrual cycle. The majority of methods for hormone measurement in the urine are cumbersome and timeconsuming. In many instances, timed specimens must be used which may be incorrectly timed or incorrectly collected.
