ABSTRACT
In previous chapters, synthetic strategies towards, and the properties of, aromatics containing the most important fluorinated substituents, namely fluorine itself and the trifluoromethyl group, have been discussed. The trifluoromethylthio and trifluoromethylsulfonyl groups have also been discussed. Other ring substituents, although less well studied, also have an important role in modem aromatic fluorine chemistry. Of these, the trifluoromethoxy, perfluoroalkyl, and fluoroalkyl side chains are probably the most important. There is currently a growing interest in the preparation of aromatics containing these groups for a number of applications, including the polymer, agrochemical, and pharmaceutical industries. These fluorinated compounds often show many of the enhanced properties that result from aromatic fluorination or trifluoromethylation. The major drawbacks associated with the incorporation of fluorinated ring substituents other than the trifluoromethyl group have been either the expense of the reagents involved, poor yields achieved, or the harsh reaction conditions required.
