ABSTRACT
IX . A Hypothetical Model for the Complex Formed Between C1 and C1-................ Inhibitor and its Possible Role in the Activation of Complement 13
XI . Acknowledgments ............................................................... 15
I. INTRODUCTION
This chapter will focus upon the remarkable structure of the first component of complement, C l , and upon its interactions with Cl-inhibitor and with antibody. A comprehensive review of C1 has just appeared;" therefore, we will concentrate on experimental studies published after the writing of that review and a hypothetical, but particularly satisfying, model for the structure of C l , variants of which have been proposed by three different laboratories.
