ABSTRACT
Xanthine oxidase from bovine milk produces substantial amounts of O2 − when acting aerobically on either purine or aldehyde substrates. The O2 − released during the aerobic action of this enzyme can exert numerous effects including initiation of free radical chain reactions, induction of chemiluminescence, and the reduction of cytochrome c. Indeed it was the exploration of these phenomena which led to the discovery of enzymic O2 − production. 1
