ABSTRACT

I have reviewed most of the relevant data on human milk lipids for preparation of this book, and given my opinions about the validity of the information. Throughout the book areas that should be investigated further have been indicated. Among those I believe to be of greatest importance are (1) fat-soluble vitamins, (2) interrelationships of nutrients with the fat globule surface area, (3) milk volume estimates, (4) biochemical indicators of lactation success, (5) the concept of compartmentalization and interrelationships thereof, (6) detailed analyses of the milk fat globule membrane, (7) physicochemical properties of the milk fat emulsion, (8) simplified methods of analysis for small quantities of milk (1 ml or less), (9) improved analyses for LC-PUFA, (10) determination of microlipids (e.g., gangliosides), (11) microbiocidal effects of milk lipids, and (12) effect of diet on the structure of TG, etc. There are many more, but these should keep us busy for some time. While milk is very complex, reliable data can be obtained with appropriate experimental design, proper sampling, and the best analytical methods available. I suggest to my colleagues that they consider the criteria above when planning research on the composition of human milk.