ABSTRACT

E. P. Ralli and G. J. Friedman recorded the occurrence of coronary occlusion in a 45-year-old man with piled up, bleeding, ulcerated gums and petechiae over both arms due to scurvy. Ascorbic acid deficiency is normally considered as a cause of haemorrhage rather than thrombosis. J. T. Salonen and P. Puska, at the University of Kuopio, have demonstrated a positive correlation between elevated serum total cholesterol levels and an increased risk of death from acute myocardial infarction in eastern Finnish men. C. A. Paterson observed some degree of haemorrhage into the intimal tissue in all of ten thrombosed coronary arteries and noted collections of hemosiderin in the deep layers of the coronary arteries in older thromboses. Serial sections of more than 100 thrombosed coronary arteries by H. Horn and L. E. Finkelstein at Mt. Sinai Hospital, New York, confirmed that intramural haemorrhage is the most frequent underlying mechanism in coronary occlusion.