ABSTRACT
420Nanotechnology in cosmetics assists consumers in looking more attractive through enhanced delivery with intradermal penetration. The application of materials in the nanometric range is responsible for the enhancement of physical, chemical, and biological properties as compared to that of coarse particles. The use of nanoparticles in cosmetic products needs a lot of attention in terms of its assessment and evaluation as cosmetics are in direct contact with the skin. This chapter discusses the determination of the physicochemical properties of nanoparticles for safety assessments and toxicological studies, along with international test guidelines. During the preparation of cosmetics, the assessment of the ingredient/s should be done very carefully so that the final products do not produce unintended harmful effects. After launching cosmetic products in the market, reevaluation is also necessary as safety assessment is a continuous process. Raw materials and other ingredients used in the cosmetic preparation should be properly selected based on characterizations of these materials using different analytical techniques. Finally, this chapter discusses international regulatory guidelines and the post-marketing analysis of cosmetic products in different countries. It will be useful for the cosmetic industry and their product safety evaluations during development, manufacturing, and submission of the products for approval.
