ABSTRACT

Biological nanomotors were once classified as linear and rotation motors. Studies on the phi29 motor led to the discovery of the third category of revolving biomotors, which is further found to be widespread among bacteria, eukaryotic viruses, and dsDNA bacteriophages. Scientists solved a decade-old puzzle in finding that this motor does not display rotational motion as it had long been believed; rather, it moves the DNA via a revolving mechanism, with the DNA being pushed through the central channel of the motor, which revolves around the DNA, into the procapsid of a bacteriophage.