ABSTRACT
Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) is a rare dermatological emergency. Though rare, risks of acute skin failure are high. SJS/TEN is primarily drug induced, which accounts for around 85% of cases, followed by infections like mycoplasma and herpes. It is considered as a spectrum with overlapping conditions. The spectrum includes SJS, SJS/TEN overlap, and TEN, depending on the extent of involvement. It is clinically characterized by a prodrome of nonspecific symptoms followed by severe mucocutaneous erosions, later complicated by systemic involvement, which is the main cause for mortality. Due to the high mortality risks and long-term complications, early diagnosis with effective prompt treatment is necessary. Management includes immediate initial assessment with history, examination, and necessary investigations, and prompt effective treatment with supportive care and disease-modifying therapy. SCORTEN is an effective tool for the assessment of severity and mortality. Since TEN is commonly associated with systemic complications, a multidisciplinary approach to the case will be rewarding to the patient and the doctor.
