ABSTRACT

Gastrointestinal cancer refers to a spectrum of cancers of the gastrointestinal tract and accessory organs of digestion, including cancers of the esophagus, stomach, small intestine, colon, rectum, liver, pancreas and gallbladder. By redefining the role of medical imaging as a data source for precision medicine through image-based phenotyping, radiomics has emerged as a powerful technique and an explosively growing, promising field in medical imaging that has deepened our understanding of cancer heterogeneity without imposing an additional imaging burden. Rapid progress in the use of radiomics for gastrointestinal cancers has been made, with a handful of studies reported to have revealed important information for differential diagnosis, histological grading and subtyping, and prediction of clinical outcome or treatment response assessment. This chapter is restricted to the radiomics research in gastrointestinal cancers and is aimed at discussing the previous studies, summarizing their results, and identifying the remaining challenges and areas where further studies are required.