ABSTRACT
The common denominator of most assisted reproduction technologies (ARTs) is ovarian (hyper)stimulation. The scheme to expose excess female gametes to abundant sperm intended to increase fertilization may inadvertently produce multiple zygotes. In ovulation induction, the number of fertilized eggs is uncontrolled and unpredicted. By contrast, the number of zygotes transferred in ART cycles has been always under control. Consequently, multiple pregnancies following ART cycles are almost exclusively physician-made (i.e., iatrogenic multiple pregnancies [IMPs]).
