ABSTRACT
INTRODUCTION Although the first baby born aer in vitro fertilization (IVF) was conceived in a non-stimulated cycle (1), it was soon accepted that the role of IVF, as an efficient therapeutic modality for subfertile couples, could only be served through multifollicular development, achieved with the use of gonadotropins (2). Gonadotropin use, however, was frequently associated with premature luteinizing hormone (LH) surge prior to oocyte retrieval, which led to cycle cancellation in approximately one out of ve women (3,4).
