ABSTRACT
Discerning and understanding structure-function relationships is often predicated on our ability to measure these properties over a range of relevant length scales. A key concept in the fields of nanoscience and nanotechnology is that directly manipulating atomic and molecular interactions in matter can ultimately control a material’s macroscopic physical, chemical, and electronic properties. This is often a consequence of understanding how complex molecular architectures, be they organic, inorganic, or biological, are derived from their constituent building blocks. To study phenomena at such a basic level, tools capable of performing functional measurements, in real time, over critical length scales are required. Such tools would enable researchers to visualize complex biomolecular structures, ideally in their native context, while simultaneously mapping their functional properties.
