ABSTRACT

This chapter begins with the introduction of intracortical neural recording microsystems and focuses on the neural signal processing approaches that are used in such systems in order to allow for high-density recording of neural signals from the brain. It focuses on the techniques employed in wireless implantable neural recording microsystems in order to enable them to handle multichannel intracortical extracellular recording of neural signals. The chapter deals with signal-level approaches to high-density neural recording, the majority of which can be categorized into two main classes: time-domain methods and transform-domain methods. It discusses the methods used in the time domain for the reduction of the amount of neural data while preserving the useful information they carry. Intracortical recording of neuronal activities is commonly performed by using penetrating microprobes. High-density neural recording from a certain region of the brain with high spatial resolution requires three-dimensional arrays of microprobes, typically made using microfabrication processes.