ABSTRACT

Organic chemistry research is a dynamic field mainly concerned with developing and applying new methods for making molecules, understanding their reactivity, and enhancing knowledge in other research fields. The application of organic chemistry research and education programs into an integrated transdisciplinary program is important for good research. In 2012, two biologists, Professor Robert J. Lefkowitz and Professor Brian Kobika, were awarded the Nobel Prize for Chemistry. They unveiled the signaling mechanism of G protein-coupled receptors (GPCRs). These proteins belong to one of the largest families of human proteins. They are involved in many physiological activities and therefore, are targets of a number of drugs. Determination of the molecular structures of this class of receptors helps researchers to understand the actual mechanism of different cellular processes. Also lifesaving and more effective drugs can be designed.