ABSTRACT
This chapter reviews the pathophysiology, surgical procedures and current management of Legg-Calve-Perthes disease (LCPD). It suggests that both clinical and laboratory based, is fundamentally necessary on recent advances in this field, a common stem is displayed suggesting that a magnitude of research. LCPD is characterised by avascular necrosis of the proximal femoral head. The primary goal of treatment is to provide a pain-free hip whilst enabling the patient to maintain the full range of motion. Nonsurgical containment treatment with spica, casts and braces is reserved for the younger patients. Total Hip Arthroplasty (THA) for LCPD is technically challenging and difficult. THA for LCPD has less satisfactory outcomes than patients with primary osteoarthritis in general. The sequelae of LCPD can manifest as a spectrum of pathologies that contribute to femoroacetabular impingement and accelerated arthritic wear. The use of bisphosphonates in LCPD in humans remains hypothetical. Preclinical studies experimenting with bone morphogenic protein-2 have implied a role in LCPD.
