ABSTRACT
The formation of a eukaryotic mRNA involves a complex series of biochemical events. The primary transcript is not the messenger RNA, but instead it must first undergo modifications such as capping of the 5′ terminus, methylation of certain internal adenylate residues, the addition of poly (A) at specific 3′ termini, and the splicing together of sequences that are noncontiguous in the genome. 1,2,3 Finally, the fully processed mRNA must then be actively transported from the nucleus to the cytoplasm in order to function in directing the synthesis of some particular protein.
