ABSTRACT

Rabies is an international problem found in the arctic, temperate, and tropical zones of the world. Those few areas free of rabies are usually isolated ecologically (primarily islands), or areas where intensive human intervention has eliminated the disease and prevented its reestablishment. The disease is not easily controlled and frequently spreads both within and between countries. It has a broad host range (theoretically including all warm-blooded animals), it has a long and variable incubation period, and infection in an individual animal is often not readily recognized in the early stages, thus delaying control efforts and promoting further spread.