ABSTRACT
The hierarchy was complicated by the discovery that even the quanta, T. H. Morgan’s genes, were themselves subdivisible by the same process of recombination that seemed to define them for Morgan. Population geneticists are often accused of having failed to incorporate the findings of modern molecular genetics. Nearly the entire corpus of literature in theoretical population genetics is written from the standpoint of single Mendelian genes or else genes that all obeyed the law of independent segregation. Since 1956, there has been an exponentially increasing attention paid to the problems posed for theoretical population genetics by the linkage of genes. The genetical evolution of a population in time can be represented as the movement of ‘particle’ in hyper-space, the location of the ‘particle’ giving the genetical composition of the population. The effect of a gene substitution at each locus separately must be very small when there are so many genes segregating for fitness traits.
