ABSTRACT
The full potential of magnetic resonance microscopy has yet to be achieved. Higher magnetic fields and advances in microcoil and circuitry designs will lead to further improvements in sensitivity and spatial resolution. A growth is observed in the use of cryogenic probes facilitated by progress in cooling technologies, allowing enhanced thermal stability and insulation. It is conceivable that much higher static magnetic fields will be made available through the development of pulsed field magnets. Biological systems containing large cells such as the Aplysia will continue to be investigated, and the scope of such investigations will be enlarged. As an example, these could include the assessment of anatomical, functional, and molecular modifications induced by behavioral changes. Anatomical imaging of fixed, isolated mammalian brain tissue with cellular and subcellular resolutions is already a reality The possibility of imaging and even performing functional studies of single mammalian neurons is within reach.
