ABSTRACT

In Chapter 18, “Fentanyl and Related Opioids: New Trends, Dangers, and Management”, Esther Papaseit, Magí Farré, Clara Pérez-Mañá, Adriana Farré, Francina Fonseca, and Marta Torrens discuss the irruption of the new fentanyl derivatives and related opioids as an heterogeneous group of non-therapeutic opioids classified as novel/new synthetic opioids (NSOs), which refers to a category of new psychoactive substances (NPSs) that are either known to be opioids or have opioid-like effects. Authors review the emergence and misuse of fentanyl and NSOs, their clinical pharmacological similitude to classical opioids and their potential for harm, and the clinical management and prevention of intoxication/overdose.