ABSTRACT

Modifiers for allostery are ‘modulators’ and modifier molecules in intervention schemes (Chapters 2 and 3) are designated ‘interventors’. The modifiers, including interventors, may be either stimulative or inhibitory. Figs. 14.1, 14.2 and Table 14.1 specify the use of nomenclature, differentiating primary ligands from modulators and interventors as well as from ‘effectors’. The separate use of ‘modulator’ and ‘interventor’ for modifier ligands in models is further detailed in Section 14.3.1.