ABSTRACT
Derivation of formulas for the intervention model in enzymology started early with Michaelis (1914) and continued in the 1950s (Table 2.1) (Laidler & Socquet 1950; Segal et al. 1952; Botts & Morales 1953; Friedenwald & Maengwyn-Davies 1954a,b, pp. 154190; Arie¨ns et al. 1955; Laidler 1956, 1958, pp. 7893; Webb 1963, pp. 5460; Cleland 1963; Hijazi & Laidler 1973; Laidler & Bunting 1973; Cha 1975).1
