ABSTRACT
Flagellate dermatitis (FD) was described by Moulin and his team in 1971. Differential diagnoses of FD include contact dermatitis, herpes zoster, digitate dermatosis, and drug eruptions. Histopathological evaluation of acute bleomycin-induced FD shows findings similar to those found in the acute phase of fixed drug eruption. The initial management of FD includes withdrawal of the drug and use of symptomatic medication for itch relief. Dermatomyositis, an autoimmune disease that affects predominantly skin and muscles may be associated with FD, besides the classic symptoms. Allergic contact dermatitis, shiitake dermatitis (SD) (toxicoderma), or FD induced by shiitake intake— and contact urticarial— are skin presentations that can be triggered by mushrooms. The main differential diagnoses of FD include chemotherapy reactions and connective tissue diseases, which can also evolve with the manifestations of FD. Symptomatic therapy with topical, and sometimes systemic, corticosteroids, besides itch control with antihistamine administration to avoid skin traumas, may be helpful.
