ABSTRACT
Microorganisms such as bacteria, fungi, cyanobacteria, and algae are valuable sources of biologically active compounds with agricultural, industrial, food, and drug potential. Numerous chemotherapeutic compounds derived from microbial sources have revealed novel mechanisms of action in clinical trials. Many studies have proved that compounds extracted from microbial origins exhibited various anti-infective activities, such as antibacterial, antifungal, antiprotozoal, and antiviral activities. Leishmaniasis is a neglected infectious disease caused by protozoan parasites of the genus Leishmania, which affects 12 million people worldwide. Finding approaches to discover new antileishmanial compounds is a pressing concern for global health programs. In this book chapter, we will present the microbial products (bacteria, fungi, cyanobacteria, and algae) that are active against Leishmania spp.
