ABSTRACT
Black flies (Simuliidae) are the second most medically important group of insects. Many adult female black fly species feed on the blood of humans and animals, and can transmit several diseases including human onchocerciasis. The present study has been primed to describe the existing data on the information on the microbial approaches for black fly-targeted onchocerciasis control. An electronic database search was done for collecting the data. Administration of ivermectin with endosymbiotic Wolbachia significantly controlled parasite development. The available literatures found in the database showed that Bacillus thuringiensis and trichomycetes are the most effective parasites of black fly adults and larvae. Effective ongoing black fly control with microbial applications achieved the target level, and the incessant research to adjust and develop control programs of black fly is essential due to climate change and anthropogenic impact.
