ABSTRACT

Vector-borne diseases continue to create serious public health threats in Southeast Asia and Western Pacific regions. Mosquitoes, sandflies, ticks, fleas, triatomine bugs, tsetse flies, blackflies, and aquatic snails carry sicknesses easily transmitted to people. Among these vectors, a kind of the mosquito—Aedes aegypti—carries the dengue virus belonging to the genus Flavivirus, family Flaviviridae. The results of previous studies have pointed out that compounds isolated, especially from microorganisms, are highly promising for the treatment of this disease. Furthermore, phytochemicals with mosquitocidal activity are recognized as potent alternative insecticides to replace synthetic insecticides in mosquito control programs due to their excellent larvicidal, pupicidal, and adulticidal properties. Therefore, in this chapter, we also reviewed the important studies on plants, lichens, algae, and natural compounds having antiflaviviral and larvicidal activity.